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LUNA-FL™双荧光细胞计数仪

LUNA-FL配备双荧光和明场光学系统,是一个功能强大的设备。LUNA-FL不受细胞类型或大小的限制,可以计数细胞,计算细胞活率和GFP转染效率。


LUNA™系列帮助世界各地的科学家获得准确和有意义的细胞数量和活力数据。

浏览一下LUNA™细胞计数家族参与的一些研究。

LUNA™自动细胞计数仪

LUNA-FL™双荧光细胞计数仪

LUNA-II™自动细胞计数仪

LUNA-STEM™SVF自动细胞计数仪

LUNA-FL™全自动细胞计数仪

1.Harada T, Ishimatsu Y, Hara A, Morita T, Nakashima S, Kakugawa T, Sakamoto N, Kosai K, Izumikawa K, Yanagihara K, Mukae H, Kohno S. Premedication with clarithromycin is effective against secondary bacterial pneumonia during influenza virus infection in a pulmonary emphysema mouse model. J Pharmacol 2016; doi: 10.1124/jpet.116.233932

2.Baatarsogt T, Bui VN, Trinh DQ, Yamaguchi E, Gronsang D, Thampsaisarn R, Ogawa H, Imai K. High antiviral effects of hibiscus tea extract on the H5 subtypes of low and highly pathogenic avian influenza viruses. J Vet Med Sci 2016; http://doi.org/10.1292/jvms.16-0124

3.Ramirez K, Sheridan JF. Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive-like behaviors. Brain BehavImmun 2016; doi:10.1016/j.bbi.2016.05.008

4.Vigani B, Mastracci L, Grillo F, Perteghella S, Preda S, Crivelli B, Antonioli B, Galuzzi M, Tosca MC, Marazzi M, Torre ML, Chlapanidas T. Local biological effects of adipose stromal vascular fraction delivery systems after subcutaneous implantation in a murine model. J BioactCompatPolym 2016; doi: 10.1177/0883911516635841

5.Sonoda T, Umeda K, Wang D, Namihira T, Akiyama H. Generation of atmospheric-pressure dry- and mist-plasma jets and their effects on HeLa cells. Plasma Med 2016; 10.1615/PlasmaMed.2016016219

6.Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmström A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Berstein D, Altman RB, Wu J. Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the prediction of breast cancer patients to doxorubicin-induced cardiotoxicity. Nat Med 2016;22:547-556

7.Wagner T, Greschik H, Burgahn T, Schmidtkunz K, Schott AK, McMillan J, Baranauskiene L, Xiong Y, Fedorov O, Jin J, Oppermann U, Matulis D, Schüle R, Jung M. Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform. Nuc Acids Res 2016;44:e88

8.Nagai K, Yanagawa Y, Katagiri S, Nagano M. The relationship between antral follicle count in a bovine ovary and developmental competence of in vitro-grown oocytes derived from early antral follicels. Biomed Res 2016;37:63-71

9.Mun JY, Shin KK, Kwon O, Lim YT, Oh DB. Minicirclemicroporation-based non-viral gene delivery improved the targeting of mesenchymal stem cells to an injury site. Biomaterials 2016;101:310-320

10.Chen YC, Ingram PN, Fouladdel S, McDermott S, Azizi E, Wicha MS, Yoon E. High-throughput single-cell derived sphere formation for cancer stem-like cell identification and analysis. Sci Rep 2016;6:27301

11.Kono K, Hiruma H, Kobayashi S, Sato Y, Tanaka M, Sawada R, Niimi S. In vitro endothelialization test of biomaterials using immortalized endothelial cells. PLoS One 2016;11:e0158289

12.Jensen AR, Manning MM, Khaneki S, Drucker NA, Markel TA. Harvest tissue source does not alter the protective power of stromal cell therapy following intestinal ischemia and reperfusion injury. J Surg Res 2016;204:361-370

13.Park D, Ha IJ, Park SY, Choi M, Lim SL, Kim SH, Lee JH, Ahn KS, Yun M, Lee SG. Morusin induces TRAIL Sensitization by regulating EGFR and DR5 in human glioblastoma cells. J Nat Products 2016;79:317-323

14.Mansfield S, Dwivedi V, Byrd S, Trgovcich J, Griessl M, Gutknecht M, Cook C. Broncholaveolar lavage to detect cytomegalovirus infection, latency, and reactivation in immune competent hosts. J Med Virol 2016;88:1408-1416

15.Kim JY, Choi K, Shaker MR, Lee JH, Lee B, Lee E, Park JY, Lim MS, Park CH, Shin KS, Kim H, Geum D, Sun W. Promotion of cortical neurogenesis from the neural stem cells in the adult mouse subcallosal zone. Stem Cells 2016;34:888-901.

16.Kim EO, Kang SE, Im CR, Lee JH, Ahn KS, Yang WM, Um JY, Lee SG, Yun M. Tanshinone IIA induces TRAIL sensitization of human lung cancer cells through selective ER stress induction. Int J Oncol 2016;48:2205-2212.

17.Richer L, Potula HH, Melo R, Vieira A, Gomes-Solecki M. A mouse model for sublethalLeptospira infection. Infect Immun 2015;83:4693-4700.

18.Yang Y, Kanno C, Huang W, Kang SS, Yanagawa Y, Nagano M. Effect of bone morphogenetic protein-4 on in vitro growth, steroidogenesis and subsequent developmental competence of the oocyte-granulosa cell complex derived from bovine early antral follicles. Reprod Biol Endocrinol 2016;14:3

19.Ramirez K, Niraula A, Sheridan JF. GABAergic modulation with classical benzodiazepines prevent stress-induced neuro-immune dysregulation and behavioral alterations. Brain BehavImmun 2016;51:154-168.

20.Kim SI, Kim HJ, Lee HJ, Lee K, Hong D, Lim H, Cho K, Jung N, Yi YW. Application of a non-hazardous vital dye for cell counting with automated cell counters. Anal Biochem. 2016;492:8-12.

21.Markel TA, Crafts TD, Jensen AR, Husberger EB, Yoder MC. Human mesenchymal stromal cells decrease mortality following intestinal ischemia and reperfusion injury. J Surg Res 2015;

22.Kim KY, Lee G, Yoon M, Cho EH, Park CS, Kim MG. Expression analyses revealed thymic stromal co-transporter/Slc46A2 is in stem cell populations and is a putative tumor suppressor. Mol Cells 2015;38:548-561

23.Kondo H, Miyoshi K, Sakiyama S, Tangoku A, Noma T. Differential regulation of gene expression of alveolar epithelial cell markers in human lung adenocarcinoma-derived A549 clones. Stem Cells Int 2015;2015:165867

24.Yi YW, You K, Bae EJ, Kwak SJ, Seong YS, Bae I. Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6. Int J Oncol 2015;47

25.Ramirez KG, Shea DT, McKim DB, Reader BF, Sheridan JF. Imipramine attenuates neuroinflammatory signaling and reverses stress-induced social avoidance. Brain BehavImmun 2015;46:212-220.

26.Yi YW, Kang HJ, Bae EJ, Oh S, Soeng YS, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTORC2 inhibitors in triple-negative breast cancer cells. Exp Mol Med 2015;47:e143.

27.Hong D, Lee G, Jung NC, Jeon M. Fast automated yeast cell counting algorithm using bright-field and fluorescence microscopic images. Biol Proced Online 2013;15:13.


LUNA™ 全自动细胞计数仪

1.Saloustros E, Liu S, Mertz EL, Bhattacharyya N, Starost MF, Salpea P, Nesterova M, Collins M, Leikin S, Stratakis CA. Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects. Mol Cell Endocrinol 2016; doi:10.1016/j.mce.2016.08.004.

2.Zhang H, Yu N, Zhou Y, Ma H, Wang J, Ma X, Liu J, Huang J, An Y. Construction and characterization of osteogenic and vascular endothelial cell sheets from rat adipose-derived mesenchymal stem cells. Tissue Cell 2016;doi:10.1016/j.tice.2016.07.004.

3.Cho YS, Hong MW, Jeong HJ, Lee SJ, Kim YY, Cho YS. The fabrication of well-interconnected polycaprolactone/hydroxyapatite composite scaffolds, enhancing the exposure of hydroxyapatite using the wire-network molding technique. J Biomed Mater Res 2016; DOI: 10.1002/jbm.b.33769.

4.Sultana N, Lazi A, Sun T. PEDOT: PSS-containing nano hydroxyapatite/chitosan conductive bionanocomposite scaffold: fabrication and evaluation. J Nanomaterials. 2016;.

5.Tanaka G, Inoue KI, Shimizu T, Akimoto K, Kubota K. Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells. Cancer Med 2016; 10.1002/cam4.844.

6.Podgórna K, Jankowska K, Szczepanowicz K. Polysaccharide gel nanoparticles modifies by the Layer-by-Layer technique for biomedical applications. Colloids Surf APhysicochemEng Asp 2016; doi:10.1016/j.colsurfa.2016.07.067.

7.Mahmoud A, Elif GE, Gül Ö. Copper (II) oxide nanoparticles induced nephrotoxicity in vitro conditions. ApplIn Vitro Toxicol 2016; doi:10.1089/aivt.2016.0008.

8.Abudayyak M, Gurkaynak TA, Özhan G. In vitro toxicological assessment of cobalt ferrite nanoparticles in several mammalian cell types. Biol Trace Element Res 2016; 10.1007/s12011-016-0803-3.

9.Gergics P, Christian HC, Choo MS, Ajmal A, Camper SA. Gene expression in mouse thyrotrope adenoma: transcription elongation factor stimulates proliferation. Endocrinology 2016; doi: 10.1210/en.2016-1183.

10.Kazemi Z, Bergmayr C, Prchal-Murphy M, Javaheri T, Themann M, Pham HTT, Strohmaier W, Sexl V, Freissmuth M, Zebedin-Brandl E. Repurposing treprostinil for enhancing hematopoietic progenitor cell transplantation. Mol Pharmacol 2016; DOI: 10.1124/mol.116.103267.

11.Gho CG, Schomann T, de Groot SC, Frijns JHM, Rivolta MN, Neumann MHA, Huisman MA. Isolation, expansion and neural differentiation of stem cells from human plucked hair: a further step towards autologous nerve recovery. Cytotechnology 2015; DOI: 10.1007/s10616-015-9938-x.

12.Burridge PW, Holmström A, Wu JC. Chemically defined culture and cardiomyocyte differentiation of human pluripotent stem cells. CurrProtoc Hum Genet 2015; doi: 10.1002/0471142905.hg2103s87.

13.Du J, Kang Y, Zhao Y, Zheng W, Zhang Y, Lin Y, Wang Z, Wang Y, Luo Q, Wu K, Wang F. Synthesis, characterization, and in vitro antitumor activity of ruthenium(II) polypyridyl complexes tethering EGFR-inhibiting 4-anilinoquinazolines. Inorg Chem 2016;55:4595-4605.

14.Sakuma T, Nakade S, Sakane Y, Suzuki KI, Yamamoto T. MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems. Nat Protocols 2016;11:118-133.

15.Marelli MM, Marzagalli M, Moretti RM, Beretta G, Casati L, Comitato R, Gravina GL, Festuccia C, Limonta P. Vimin E δ-tocotrienol triggers endoplasmic reticulum stress-mediated apoptosis in human melanoma cells. Sci Rep 2016;6:30502.

16.Muter J, Brighton PJ, Lucas ES, Lacey L,Shmygol A, Quenby S, Blanks AM, Brosen JJ. Progesterone-dependent induction of phospholipase C-related catalytically inactive protein 1 (PRIP-1) in decidualizing human endometrial stromal cells. Endocrinology 2016;157:2883-2893.

17.Ishibashi D, Nakagaki T, Ishikawa T, Atarashi R, Watanabe K, Cruz FA, Hamada T, Nishida N. Structure-based drug discovery for prion disease using a novel binding simulation. EBioMedicine 2016;9:238-249. 

18.Nishimura K, Watanabe S, Hayashida R, Sugishima S, Iwasaka T, Kaku T. Binucleated HeLa cells are formed by cytokinesis failure in starvation and keep the potential of proliferation. Cytotechnology 2016;68:1123-1130.

19.Szczepanowicz K, Jantas D, Piotrowski M, Staroń J, Leśkiewicz M, Regulska M, Lasoń W, Warszyński P. Encapsulation of curcumin in polyelectrolyte nanocapsules and their neuroprotective activity. Nanotechnology 2016;27:355101.

20.Sugo N, Yamamoto N. Visualization of HDAC9 spatiotemporal subcellular localization in primary neuron cultures. Methods Mol Biol 2016;1436:119-127.

21.Andree KC, Barradas AMC, Nguyen AT, Mentink A, Stojanovic I, Baggerman J, van Dalum J, van Rijn CJM, Terstappen LWMM. Capture of tumor cells on anti-EpCAM-functionalized poly(acrylic acid)-coated surfaces. ACS Appl Mater Interfaces 2016;8:14349-14356.

22.Wrotek S, Jędrzejewski T, Piotrowski J, Kozak W. N-acetyl-L-cysteine exacerbates generation of IL-10 in cells stimulated with endotoxin in vitro and produces antipyresis via IL-10 dependent pathway in vivo. Immunol Lett 2016;177:1-5.

23.Mahmoud A, Ezgi Ö, Merve A, Özhan G. In vitro toxicological assessment of magnesium oxide nanoparticle exposure in several mammalian cell types. Int J Toxicol 2016;35:429-437.

24.Feng WM, Guo HH, Xue T, Wang X, Tang CW, Bao Y, Gong H, Cui G. Polyelectrolyte multilayer assembled from IL-10 plasmid DNA and TGF-β siRNA facilitates chronic pancreatitis treatment. RSC Adv 2016;6:60171-60179.

25.Jo DH, Hong JW, Kim JH, Han SW, Kim JH. Gold nanocrystals with well-defined crystallographic {111} facets suppress pathological neovascularization. J Biomed Nanotechnol 2016;12:1520-1526.

26.Kowalczewska M, Piotrowski J,Jędrzejewski T, Kozak W. Polysaccharide peptides from Coriolus versicolor exert differential immunomodulatory effects on blood lymphocytes and breast cancer cell line MCF-7 in vitro. Immunol Lett 2016;174:37-44.

27.Kim SH, Kim EC, Kim WJ, Lee MH, Kim SY, Kim TJ. Coptis Japonica makino extract suppresses angiogenesis through regulation of cell cycle-related proteins. BiosciBiotechnol Biochem 2016;80:1095-1106.

28.Cataldo LR, Mizgier ML, Busso D, Olmos P, Galgani JE, Valenzuela R, Mezzano D, Aranda E, Cortés VA, Santos JL. Serotonin- and dopamine-related gene expression in db/db mice islets and in MIN6 β-cells treated with palmitate and oleate. J Diabet Res. 2016;2016:3793781.

29.Wijnholds J, Pellissier LPF. Recombinant AAV-crumbs homologue composition and method for treating LCA-8 and progressive RP. US Patent Application 2016019474.

30.Ra JC, Kang SK, Jo JY; Culture medium composition for improving regenerative capacity of stem cells, and stem cell culturing method using same. US Patent Application 20160090573.

31.Babich JW, Shawn H, Joyal J; Molecular Insight Pharmaceuticals, Inc. Organ protection in PSMA-targeted radionuclide therapy of prostate. US Patent Application 20160067361.

32.Lee JH, Om IY, Kim YH, Kim KM, Choi EH, Kim KN. Selective killing effects of cold atmospheric pressure plasma with NO induced dysfunction of epidermal growth factor receptor in oral squamous cell carcinoma. PLoS One 2016;11:e0150279.

33.Liu S, Saloustros E, Berthon A, Starost M, Sahut-Barnola I, Salpea P, Szarek E, Faucz FR, Martinez A, Stratakis CA. Celecoxib reduces glucocorticoids in vitro and in a mouse model with adrenocortical hyperplasia. EndocrRelat Cancer 2016;23:15-25.

34.Svensson D, Wilk L, Mörgelin M, Herwald H, Nilsson BO. LL-37-induced host cell cytotoxicity depends on cellular expression of the gluobular C1q receptor (p33). Biochem J 2016;473:87-98.

35.Salimath MB, Shobha KS, Onkarappa R. Anti-lymphocytic enzyme L-asparaginase from Streptomyces antitioticus of Western Ghat Soil. Int ConfAdvBiotechnol (BioTech) Proc 2016;40-46.

36.Cheng XB, Kohi S, Koga A, Hirata K, Sato N. Hyaluronan stimulates pancreatic cancer cell motility. Oncotarget 2016;7:4829-4840.

37.Gispert C, Serrà A, Alea ME, Rodrigues M, Gómez E, Mora M, Sagristá MLI, Pérez-García L, Vallés E. Electrochemical preparation and characterization of magnetic core-shell nanowires for biomedical applications. Electrochem Commun 2016;63:18-21.

38.Otsuka R, Harada N, Aoki S, Shirai K, Nishitsuji K, Nozaki A, Hatakeyama A, Shono M, Mizusawa N, Yoshimoto K, Nakaya Y, Kitahata H, Sakaue H. C-terminal region of GADD34 regulates eIF2α dephosphorylation and cell proliferation in CHO-K1 cells. Cell Stree Chaperones 2016;21:29-40.

39.Nagata H, Il M, Kohbayashi E, Hoshiga M, Hanafusa T, Asahi M. Cardiac adipose-derived stem cells exhibit high differentiation potential to cardiovascular cells in C57BL/6 mice. Stem Cells Tansl Med 2016;5:1-11. 

40.Kim SI, Kim HJ, Lee HJ, Lee K, Hong D, Lim H, Cho K, Jung N, Yi YW. Application of a non-hazardous vital dye for cell counting with automated cell counters. Anal Biochem. 2016;492:8-12.

41.Kang HJ, Yi YW, Hou SJ, Kim HJ, Kong Y, Bae I, Brown ML. Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor. Oncotarget 2015; DOI: 10.18632/oncotarget.4054.

42.Şenyildiz M, Őzden S. Alteration in global DNA methylation after bisphenol a exposure in MCF-7 cells. J Fac Pharm Istanbul 2015;45:153-164.

43.Feng WM, Gu HH, Xue T, Wang X, Tang CW, Ying B, Gong H, Cui G. Anti-inflammation and anti-fibrosis with PEGylated, apigenin loaded PLGA nanoparticles in chronic pancreatitis disease. RSC Adv 2015;5:83628-83635.

44.Han AR, Lee JY, Kim HJ, Min WS, Park G, Kim SH. A CXCR4 antagonist leads to tumor suppression by activation of immune cells in a leukemia-induced microenvironment. Oncol Rep 2015;34:2880-2888.

45.Bhaskarachar RK, Revanasiddappa VG, Hegde S, Balakrishna JP, Reddy SY. Design, synthesis and anticancer activity of functionalized spiro-quinolines with barbituric and thiobarbituric acids. Med Chem Red 2015;24:3516-3528.

46.Piotrowski M, Jantas D, Szczepanowicz K, Łukasiewicz S, Lasoń W, Warszyńskia P. Polyelectrolyte-coated nanocapsules containing undecylenic acid: synthesis, biocompatibility and neuroprotective properties. Colloids Surf B Biointerfaces 2015;135:8-17.

47.Sancak D, Ozden S. Global histone modifications in fumonisin B1 exposure in rat kidney epithelial cells. Toxicol In Vitro 2015;29:1809-1815.

48.Yi YW, Park JS, Kwak SJ, Seong YS. Co-treatment with BEZ235 enhances sensitivity of BRCA1-negative breast cancer cells to olaparib. Anticancer Res 2015;35:3829-3838.

49.Hira A, Yoshida K, Sato K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shimamoto A, Tahara H, Ito E, Kojima S, Kurumizaka H, Ogawa S, Takata M, Yabe H, Yabe M. Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Faconi anemia. Am J Hum Genet 2015;96:1001-1007.

50.Kim EC, Kim SH, Bae K, Kim HS, Gelinsky M, Kim TJ. The anti-angiogenic potential of a Phellodendronamurense hot water extract in vitro and ex vivo. J Life Sci 2015;25:693-702.

51.Jantas D, Piotrowski M, Lason W. An involvement of PI3-K/Akt activation and inhibition of AIF translocation in neuroprotective effects of undecylenic acid (UDA) against pro-apoptotic factors-induced cell death in human neuroblostoma SH-SY5Y cells. J Cell Biochem 2015;116:2882-2895.

52.Uzar NK, Abudayyak M, Akcay N, Algun G, Özhan G. Zinc oxide nanoparticles induced cyto- and genotoxicity in kidney epithelial cells. Toxicol Mech Methods 2015:25:334-339.

53.Hsiao YS, Ho BC, Yan HX, Kuo C, Chueh DY, Yu HH, Chen P. Integrated 3D conducting polymer-based bioelectronics for capture and release of circulating tumor cells. J Mater Chem B Mater Biol Med 2015;3:5103-5110.

54.Kobashigawa S, Kashino G, Mori H, Watanabe M. Relief of delayed oxidative stress by ascorbic acid can suppress radiation-induced cellular senescence in mammalian fibroblast cells. Mech Ageing Dev 2015;146-148:65-71.

55.Lopez MB, Garcia MN, Grasso D, Bintz J, Molejon MI, Velez G, Lomberk G, Neira JL, Urrutia R, Inovanna J. Functional characterization of Nupr1L, a novel p53-regulated isoform of the high mobility group (HMG)-related protumoral protein Nupr1. J Cell Physiol 2015:230:2939-2950.

56.Cadena-Herrera D, Lala JEED, Ramírez-Ibañez ND, López-Morales CA, Pérez NO, Flores-Ortiz LF, Medina-Rivero E. Validation of three viable-cell counting methods: manual, semi-automated, and automated. Biotechnol Rep 2015;7:9-16.

57.Yi YW, You K, Bae EJ, Kwak SJ, Seong YS, Bae I. Dual inhibition of EGFR and MET induces synthetic lethality in triple-negative breast cancer cells through downregulation of ribosomal protein S6. Int J Oncol 2015;47:122-132.

58.Bhat M, Marar T. Cytotoxic effect of purified L-asparaginase from Salinicoccus sp. M KJ997975. Int J CurrMicrobiol App Sci 2015;4:701-712.

59.Hong MH, Choi HJ, Ko YM, Lee YK. Engineered microstructure granules for tailored drug release rate. BiotechnolBioeng 2015;112:1936-1947.

60.Pourcelot E, Lénon M, Mobilia N, Cahn JY, Arnaud J, Fanchon E, Moulis JM, Mossuz P. Iron for proliferation of cell lines and hematopoietic progenitors: nailing down the intracellular functional iron concentration. Biochim Biophys Acta 2015:1853:1596-1605.

61.Welker S, Servas C, Rui M, Götz C, Montenarth M. Tissue-specific functions and regulation of protein kinase CK2. Adv Biochem Health Dis 2015;12:109-123.

62.Yuasa M, Yamada T, Taniyama T, Masaoka T, Xuetao W, Yoshii T, Horie M, Yasuda H, Uemura T, Okawa A, Sotome S. Dexamethasone enhances osteogenic differentiation of bone marrow- and muscle-derived stromal cells and augments ectopic bone formation induced by bome morphogenetic protein-2. PLoS One 2015;10:e0116462.

63.Renner SP, Strissel PL, Beckmann MW, Lermann J, Burghaus S, Hackl J, Fasching PA, Strick R. Inhibition of adhesion, proliferation and invasion of primary endometriosis, endometrial stromal and ovarian carcinoma cells by a non-hyaluronan adhesion barrier gel. BioMed Res Int. 2015;2015:450468.

64.Kim EC, Kim HJ, Kim TJ. Water extract of Cinnamomum cassia suppresses angiogenesis through inhibition of VEGF receptor 2 phosphorylation. BiosciBiotechnol Biochem 2015;79:617-624.

65.Bahn YJ, Lee KP, Lee SM, Choi JY, Seo YS, Kwon KS. Nucleoredoxin promotes adipogenic differentiation through regulation of Wnt/β-catenin signaling. J Lipid Res 2015;56:294-303.

66.Nakamura T, Shinriki S, Jono H, Guo J, Ueda M, Hayashi M, Yamashita S, Zijlstra A, Nakayama H, Hiraki A, Shinohara M, Ando Y. Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells. Oncotarget 2015;6:1008-1019.

67.Lazra Y, Falach A, Frenkel L, Rozenberg K, Sampson SR, Rosenzweig T. Autocrine/paracrine function of globular adiponectin: inhibition of lipid metabolism and inflammatory response in 3T3-L1 adipocytes. J Cell Biochem 2015;116:754-766.

68.Nakamura T, Shinriki S, Jono H, Ueda M, Nagata M, Guo J, Hayashi M, Yoshida R, Ota T, Ota K, Kawahara K, Nakagawa Y, Yamshita S, Nakayama H, Hiraki A, Shinohara M, Ando Y. Osteopontin-integrin αvβ3 axis is crucial for 5-fluorouracil resistance in oral squamous cell carcinoma. FEBS Lett 2015;589:231-239.

69.Yi YW, Kang HJ, Bae EJ, Oh S, Soeng YS, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTORC2 inhibitors in triple-negative breast cancer cells. Exp Mol Med 2015;47:e143.

70.Yi YW, Oh S. Comparative analysis of NRF2-responsive gene expression in AsPC-1 pancreatic cancer cell line. Genes Genom 2015;37:97-109.

71.Colciago A, Melfi S, Giannotti G, Bonalume V, Ballabio M, Caffino L, Fumagalli F, Magnaghi V. Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms. Cell Death Discov 2015;1:15021.

72.Sun T, Tsan WM, Park WT, Merugu S. Surface characteristics, biodegradability and biocompatibility of porous silicon for microfabricated neural electrode. J NanosciNanotechnol 2015;15:2821-2828.

73.Siqueira PC, Magalhães APR, Pires WC, Pereira FC, Silveira-Lacerda EP, Carrião MS, Bakuzis AF, Souza-Costa CA, Lopes LG, Estrela C. Cytotoxicity of glass ionomer cements containing silver nanoparticles. J Clin Exp Dent 2015;7:e622-e627.

74.Kang HJ, Yi YW, Hong YB, Kim HJ, Jang YJ, Seong YS, Bae I. HER2 confers drug resistance of human cancer cells through activation of NRF2 by direct interaction. Sci Rep 2014;4:7201.

75.Kim EC, Kim HJ, Kim TJ. Hot-water extract of RubusCoreanus Miquel suppresses VEGF-induce angiogenesis. J Life Sci 2014;24:1345-1355.

76.Masuda T, Yilling S, Eui SW, Niimi M, Yusa A, Nakanishi H, Ara F. Cell isolation system for rare circulating tumor cell. 2014 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2014). 2014;DOI: 10.1109/IROS.2014.6943230.

77.Adimule VM. Design, synthesis and cytotoxic evaluation of novel 2-(4-N,N-dimethyl) pyridine containing 1,3,4-oxadiazole moiety. Asian J Biomed Pharmaceut Sci 2014;34:1-5.

78.Cho YS, Hong MW, Kim SY, Lee SJ, Lee JH, Kim YY, Cho YS. Fabrication of dual-pore scaffolds using SLUP (salt leaching using powder) and WNM (wire-network molding) techniques. Mat Sci Eng C 2014;45:546-555.

79.Adimule V, Medapa S, Jagadeesha AH, Kumar LS, Rao PK. Synthesis, characterization and cytotoxic evaluation of novel derivatives of 1,3,4-oxadiazole containing 5-phenyl thiophene moiety. IOSR J Pharm Biol Sci 2014;9:42-48.

80.Bieler J, Cannavo R, Gustafson K, Gobet C, Gatfield D, Naef F. Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells. Mol Syst Biol 2014;10:739.

81.Yalcin I, Horakova J, Mikes P, Sadikoglu TG, Domin R, Lukas D. Design of polycaprolactone vascular grafts. J Ind Text 2014; doi: 10.1177/1528083714540701.

82.Schnell A, Chappuis S, Schmutz I, Brai E, Ripperger J, Schaad O, Welzl H, Descombes P, Alberi L, Albrecht U. The nuclear receptor REV-ERBα regulates Fabp7 and modulates adult hippocampal neurogenesis. PLoS One 2014;9:e99883.

83.Yamanaka S, Yokote S, Yamada A, Katsuoka Y, Izuhara L, Shimada Y, Omura N, Okano HJ, Ohki T, Yokko T. Adipose tissue-derived stem cells in long-term dialysis patients display downregulation of PCAF expression and poor angiogenesis activation. PLoS One 2014;9:e102311.

84.Kim SY, Lee DH, Song X, Bartlett DL, Kwon YT, Lee YJ. Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells. Apoptosis 2014;19:1603-1615.

85.Arasada RR, Amann JM, Rahman MA, Huppert SS, Carbone DP. EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling. Cancer Res 2014;74:5572-5584.

86.Lui YLE, Tan TL, Woo WH, Timms P, Hafner LM, Tan KH, Tan EL. Enterovirus71 (EV71) utilize host microRNAs to mediate host immune system enhancing survival during infection. PLoS One 2014;9:e102997.

87.Lee JW, Kwon JS, Om JY, Kim YH, Choi EH, Kim KM, Kim KN. Cell immobilization on polymer by air atmospheric pressure plasma jet treatment. Jpn J Appl Phys 2014;53:086202.

88.Patel MN, Lakkadwala S, Majrad MS, Injeti ER, Gollmer SM, Shah ZA, Boddu SHS, Nesamony J. Characterization and evaluation of 5-fluorouracil-loaded solid lipid nanoparticles prepared via a temperature-modulated solidification technique. AAPS PharmSciTech 2014;15:1498-1508.

89.Song B, Kim B, Choi SH, Song KY, Chung YG. Lee YS, Park G. Mesenchymal stromal cells promote tumor progression in fibrosarcoma and gastric cancer cells. Kor J Pathol 2014;48:217-224.

90.Hou SJ, Yi YW, Kang HJ, Zhang L, Kim HJ, Kong Y, Liu Y, Wang K, Kong HS, Grindrod S, Bae I, Brown ML. Novel carbazole inhibits phospho-STAT3 through induction of protein tyrosine phosphatase PTPN6. J Med Chem 2014;57:6342-6353.

91.Hassan MI, Sun T, Sultana N. Fabrication of nanohydroxyapatite/poly(caprolactone) composite microfibers using electrospinning technique for tissue engineering applications. J Nanomaterials 2014;2014:209049.

92.Samara A, Galbiati M, Luciani P, Deledda C, Messi E, Peri A, Maggi R. Altered expression of 3-betahydroxysterol delta-24-reductase/selective Alzheimer’s disease indicator-1 gene in Huntington’s disease models. J Endocrinol Invest 2014;37:729-737.

93.Jo DH, Kim JH, Son JG, Piao Y, Lee TG, Kim JH. Inhibitory activity of gold and silica nanspheres to vascular endothelial growth factor (VEGF)-mediated angiogenesis is determined by their sizes. Nano Res 2014;7:844-852.

94.Kwon JS, Kim KM, Kim KN. A comparative study of three cytotoxicity test methods for nanomaterials using sodium lauryl sulfate. J NanosciNanotechnol 2014;14:8043-8047.

95.Jeong SH, Kim HK, Song IS, Lee SJ, Ko KS, Rhee BD, Kim N, Mishchenko NP, Fedoryev SA, Stonik VA, Han J. Echinochrome A protects mitochondrial function in cardiomyocytes against cardiotoxic drugs. Mar Drugs 2014;12:2922-2936.

96.Duong HQ, Yi YW, Kang HJ, Hong YB, Tang W, Wang A, Seong YS, Bae I. Inhibition of NRF2 by PIK-75 augments sensitivity of pancreatic cancer cells to gemcitabine. Int J Oncol 2014;44:959-969.

97.Lee JH, Park JW. Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of H9c2 cardiomyocytes. Biochimie 2014;99:110-118.

98.Lakkadwala S, Nguyen S, Lawrence J, Nauli SM, Nesamony J. Physico-chemical characterization, cytotoxic activity, and biocompatibility studies of tamoxifen-loaded solid lipid nanoparticles prepared via a temperature-modulated solidification method. J Microencapsul 2014;31:590-599.

99.Kim EC, Kim HJ, Kim TJ. Novel anti-angiogenic activity in Rubuscoreanus Miquel water extract suppresses VEGF-induced angiogenesis. Biomedical Sci Lett 2014;20:209-220.

100.Yusa A, Toneri M, Masuda T, Ito S, Yamamoto S, Okochi M, Kondo N, Iwata H, Yatabe Y, Ichinosawa Y, Kinuta S, Kondo E, Honda H, Arai F, Nakanishi H. Development of a new rapid isolation device for circulating tumor cells (CTCs) using 3D palladium filter and its application for genetic analysis. PLoS One 2014;9:e88821.

101.Sun T, Tsang WM, Park WT. Drug release from porous silicon for stable neural interface. Appl Surface Sci 2014;292:843-851.

102.Sun T, Khan TH, Sultana N. Fabrication and in vitro evaluation of nanosized hydroxyapatite/chitosan-based tissue engineering scaffolds. J Nanomaterials 2014;2014:194680.

103.Lee LT, Ng SY, Chu JY, Sekar R, Harikumar KG, Miller LJ, Chow BK. Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex. FASEB J 2014;28:2632-2644.

104.Hong MH, Kim SM, Om JY, Kwon N. Lee YK. Seeding cells on calcium phosphate scaffolds using hydrogel enhanced osteoblst proliferation and differentiation. Annals Biomed Eng 2014;42:1424-1435.

105.Rodrigues HF, Mello FM, Branguinho LC, Zufelato N, Silverira-Lacerda EP, Bakuzis AF. Real-time infrared thermography detection of magnetic nanoparticle hyperthermia in a murine model under a non-uniform field configuration. Int J Hyperthermia 2013;29:752-767.

106.Song HB, Jun HO, Kim JH, Yu YS, Kim KW, Min BH, Kim JH. Anti-apoptotic effect of clusterin on cisplatin-induced cell death of retinoblastoma cells. Oncol Rep 2013:30:2713-2718.

107.Yusa A, Matsumoto Y, Terazawa K, Masuda T, Arai F, Nakanishi H. Isolation of living circulating tumor cells (CTCs) from peripheral blood using size-based device and its application to CTC technology in mice. IEEE 2013 International Symposium on Micro-NanoMechatronics and Human Science (MHS). 2013;DOI: 10.1109/MHS.2013.6710455.

108.Liu YLE, Timms P, Hafner LM, Tan TL, Tan KH, Tan EL. Characterization of enterovirus 71 replication kinetics in human colorectal cell line, HT29. SpringerPlus 2013;2:267.

109.Montero D, Tachibana C, Winther JR, Appenzeller-Herzog C. Intracellular glutathione pools are heterogeneously concentrated. Redox Biol 2013;1:508-513.

110.Leung TH, Wong SC, Chan KK, Chan DW, Cheung AN, Ngan HY. The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells. Br J Cancer 2013;109:965-975.

111.Duong HQ, Hong YB, Kim JS, Lee HS, Yi YW, Kim YJ, Wang A, Zhao W, Cho CH, Seong YS, Bae I. Inhibition of checkpoint kinase 2 (CHK2) enhances sensitivity of pancreatic adenocarcinoma cells to gemcitabine. J Cell Mol Med 2013;10:1261-1270.

112.Yi YW, Kang HJ, Kim HJ, Kong Y, Brown ML, Bae I. Targeting mutant p53 by a SIRT1 activator YK-3-237 inhibits the proliferation of triple-negative breast cancer cells. Oncotarget 2013;4:984-994.

113.Yi YW, Hong W, Kang HJ, Kim HJ, Zhao W, Wang A, Seong YS, Bae I. Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of inhibitors for EGFR kinase in triple-negative breast cancer cells. J Cell Mol Med 2013;17:648-656.

114.Sajay BNG, Chan CP, Ahmad H, Chung WC, Puiu PD, Rahman ARA. Towards an optimal and unbiased approach for tumor cell isolation. Biomed Microdevices 2013;15:699-709.

115.Kwon JS, Kim YH, Choi EH, Kim KN. The effects of non-thermal atmospheric pressure plasma jet on attachment of osteoblast. CurrAppl Phys 2013;13:S42-S47.

116.Nam JO, Son HN, Jun E, Cha K, Lee BH, Park RW, Kim IS. FAS1 domain protein inhibits VEGF165-induced angiogenesis by targeting the interaction between VEGFR-2 and αvβ3 integrin. Mol Cancer Res 2012;10:1010-1020.

117.Duong HQ, Hwang JS, Kim HJ, Seong YS, Bae I. BML-275, an AMPK inhibitor, induces DNA damage, G2/M arrest and apoptosis in human pancreatic cancer cells. Int J Oncol 2012;41:2227-2236.

118.Duoung HQ, Hwang JS, Kim HJ, Kang HJ, Seong YS, Bae I. Aldehyde dehydrogenase 1A1 confers intrinsic and acquired resistance to gemcitabine in human pancreatic adenocarcinoma MIA PaCa-2 cells. Int J Oncol 2012;41:855-861.

119.Kang HJ, Yi YW, Kim HJ, Hong YB, Seong YS, Bae I. BRCA1 negatively regulates IGF-1 expression through an estrogen-responsive element-like site. Cell Death Dis 2012;3:e336.


LUNA-II™ 全自动细胞计数仪

1.Cheng YH, Chen YC, Brien R, Yoon E. Scaling and automation of high-throughput single-cell-derived tumor sphere assay chip. Lab Chip 2016; DOI: 10.1039/C6LC00778C.

2.Jeong W, Yang X, Lee J, Ryoo Y, Kim J, Oh Y, Kwon S, Liu D, Son D. Serial changes in the proliferation and differentiation of adipose-derived stem cells after ionizing radiation. Stem Cell Res Ther 2016;7:11

3.Silina YE, Fink-Staube C, Hanselmann RG, Peuschel H, Volmer DA. p-coumaric acid, a novel and effective biomarker for quantifying hypoxic stress by HILIC-ESI-MS. J Chromatography B 2016;1020:6-13.

4.Montufar EB, Horynová M, Casas-Luna M, Diaz-de-la-Torre S, Celko L, Klakurková L, Spotz Z, Diéguez-Trjo G, Fohlerová Z, Drorak K, Zikmund T, Kaiser J. Spark plasma sintering of load-bearing iron-carbon nanotube-tricalcium phosphate CerMets for orthopaedic applications. JOM 2016

5.Bochev I, Belemezova K, Shterev A, Kyurkchiev S. Effect of cryopreservation on the properties of human endometrial stromal cells used in embryo co-culture systems. J Assist Reprod Genet 2016

6.Kim SI, Kim HJ, Lee HJ, Lee K, Hong D, Lim H, Cho K, Jung N, Yi YW. Application of a non-hazardous vital dye for cell counting with automated cell counters. Anal Biochem. 2016;492:8-12.

7.Cheng YH, Chen YC, Brien R, Yoon E. Scaling and automation of high-throughput single-cell-derived tumor sphere assay chip. Lab Chip 2016; DOI: 10.1039/C6LC00778C.


LUNA-STEM™ 全自动细胞计数仪

1.Procházka V, Jurčíková J, Laššák O, Vítková K, Pavliska L, Porubová L, Buszman PP, Krauze A, Fernandez C, Jalůvka F, Špačková I, Lochman I, Jana D, Merfeld-Clauss S, March KL, Traktuev DO, Johnstone BH. Therapeutic potential of adipose-derived therapeutic factor concentrate for treating critical limb ischemia. Cell Transplant 2015; doi: 10.3727/096368915X689767.